Search results for "GBR membranes"

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Hyaluronan alkyl derivatives-based electrospun membranes for potential guided bone regeneration: Fabrication, characterization and in vitro osteoindu…

2020

Item does not contain fulltext The aim of the work was to determine the effects of the chemical functionalization of hyaluronic acid (HA) with pendant aliphatic tails at different lengths and free amino groups in terms of chemical reactivity, degradation rate, drug-eluting features, and surface properties when processed as electrospun membranes (EM) evaluating the osteoinductive potential for a possible application as guided bone regeneration (GBR). To this end, a series of HA derivatives with different aliphatic tails (DD-Cx mol% ≈ 12.0 mol%) and decreasing derivatization of free amino groups (DD(EDA) mol% from 70.0 to 30.0 mol%) were first synthesized, namely Hn. Then dexamethasone-loaded…

Whole membraneBone RegenerationDexamethasone; Electrospun nanofibers; GBR membranes; Hyaluronic acid alkylated.Nanofibers02 engineering and technologyHyaluronic acid alkylated01 natural sciencesPolyvinyl alcoholDexamethasoneGBR membranesHydrolysischemistry.chemical_compoundColloid and Surface ChemistryOsteogenesis0103 physical sciencesPhysical and Theoretical ChemistryHyaluronic AcidBone regenerationAlkylchemistry.chemical_classificationAqueous solutionMembranesElectrospun nanofibers010304 chemical physicsCyclodextrinMembranes ArtificialSurfaces and InterfacesGeneral Medicine021001 nanoscience & nanotechnologyReconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10]Membranechemistry0210 nano-technologyBiotechnologyNuclear chemistry
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